Apart from the standard procedure of enzymatic protein digestion other protocols can be performed on the protein entrapped in gel matrix. The highly flexible software allows the use of different enzymes, de-staining of silver gels, isotopic labelling of peptides as well as other chemical reactions on specific amino acids. In the MALDI part, sub-µl volumes of samples and reagents can be pipetted to different receivers such as MALDI plates or small vials.