In situ hybridization, allowing the detection of DNA and RNA, and immunohistochemistry, for localization of proteins and other antigens, are powerful techniques to explore the temporal and spatial expression pattern of genes and their products within organisms. Both techniques are primarily used in developmental biology or anatomy, but are gaining more and more importance in fields like genetics, evolutionary developmental biology, cancer research and somatic stem cell research.
In situ detection protocols are always tedious and time consuming, taking several days with laborious repeated washing and incubation steps. The InsituPro Upgrade, InsituProVS and the InsituPro VSi fully automate all steps of these methods, thus allowing the user to concentrate on new scientific challenges. The InsituStain instrument is a low-cost solution that automates most steps and saves precious time. All these robots are operated by easy-to-use operation software and delivered with a growing collection of optimized, user tested protocols.
The
InsituPro VSi is INTAVIS’ next generation instrument for automated in situ
hybridization and immunohistochemistry – it represents the third generation of
the InsituPro product line. The InsituPro VSi maintains the flexibility and
versatility of the InsituPro VS but additionally features a number of functions
often requested by our customers such as a buffer preheating for
posthybridization washes and more flexibility in temperature setting due to
direct software control of the thermoregulator.
The InsituPro VSsucceeded
the InsituPro
in our in situ detection product line, using advanced technology for
improved performance. It fully automates all steps of in situ detection
methods, allowing the user to concentrate on new scientific challenges. The InsituPro VSis
a flexible platform, helping the user to get results regardless of whether they
are working with whole mounts, vibratome sections, organs or tissue sections.
The upgrade
for the InsituPro
is an easy way to retrofit the advanced liquid handling system and mode of
operation of the InsituPro VS and InsituPro VSito the older instrument. This
allows for much gentler processing of up to 30 whole mounts or vibratome
sections or alternatively up to 24 slides.
The InsituStain automates most steps of in situ detection on whole mounts and sections. A selection of optional modules for the InsituStain makes it simple to run other applications such as Western Blotting by simply swapping modules.
